Future challenges for research on diagnostic tests: genetic tests and disease prevention

Future challenges for research on diagnostic tests: genetic tests and disease prevention.

Misguided efforts and future challenges for research on "diagnostic tests".

At the end of the second world war, the prime scientific goal in clinical medicine was to make a correct diagnosis. Its importance was demonstrated by the attention it received in medical education. Students and house staff regularly went from the hospital ward to the institutional morgue to see the diagnostic findings at necropsy. The clinicopathological conference (CPC) was a popular teaching...

Diagnostic Tests for Alzheimer's Disease: Rationale, Methodology, and Challenges

There has been a large increase in the amount of research seeking to define or diagnose Alzheimer's disease before patients develop dementia. If successful, this would principally have clinical benefits both in terms of treatment as well as risk modification. Moreover, a better method for diagnosing predementia disease would assist research which seeks to develop such treatments and risk modifi...

Prenatal diagnostic tests of genetic disorders: review article

The purpose of prenatal diagnosis tests is insisting of diagnosis of neonatal disorders, preparing a range of informed choices and making couples at risk to be ready for having children with genetic disorders as well. The aim of this article is to investigate all of the tests in order to determine the best one which has the lowest risk and the highest sensitivity. Screening tests (maternal bloo...

Risk perception, prevention and diagnostic tests.

The objective of this paper is to study the impact of risk perception and diagnostic information on medical prevention decisions. The intertemporal preferences of individuals are represented by a model of recursive rank dependent utility, which has the advantage of allowing risk perceptions to vary over time and with health status. The main results of the paper are the following. Concerning the...